Massimiliano Cadamuro Selected Research

Congenital Hepatic Fibrosis

1/2022	Dysregulation of the Scribble/YAP/β-catenin axis sustains the fibroinflammatory response in a PKHD1-/- mouse model of congenital hepatic fibrosis.
1/2018	β-Catenin and interleukin-1β-dependent chemokine (C-X-C motif) ligand 10 production drives progression of disease in a mouse model of congenital hepatic fibrosis.
11/2013	Protein kinase A-dependent pSer(675) -β-catenin, a novel signaling defect in a mouse model of congenital hepatic fibrosis.

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Massimiliano Cadamuro Research Topics

Disease

14	Neoplasms (Cancer) 01/2022 - 09/2011
13	Cholangiocarcinoma 01/2022 - 09/2011
8	Inflammation (Inflammations) 04/2022 - 12/2015
7	Cysts 01/2022 - 05/2006
6	Fibrosis (Cirrhosis) 01/2022 - 01/2011
5	Liver Diseases (Liver Disease) 01/2021 - 05/2006
3	Congenital Hepatic Fibrosis 01/2022 - 11/2013
3	Polycystic liver disease 06/2021 - 01/2010
3	Glioma (Gliomas) 01/2019 - 01/2017
2	Carcinogenesis 01/2022 - 01/2022
2	Insulin Resistance 01/2022 - 01/2011
2	Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I) 01/2021 - 01/2018
2	Sclerosing Cholangitis 01/2019 - 01/2019
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2019 - 01/2018
2	Cystic Fibrosis (Mucoviscidosis) 01/2019 - 01/2019
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2018 - 03/2016
2	Hypoxia (Hypoxemia) 12/2015 - 01/2010
2	Autosomal Dominant Polycystic Kidney (ADPKD) 05/2010 - 05/2006
2	Body Weight (Weight, Body) 05/2010 - 01/2010
1	Necrosis 04/2021
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2021
1	Ciliopathies 01/2021
1	Rare Diseases (Rare Disease) 01/2021
1	Reperfusion Injury 01/2020
1	Cholestasis 01/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Glioblastoma (Glioblastoma Multiforme) 01/2019
1	Lymphatic Metastasis 01/2019
1	Schizophrenia (Dementia Praecox) 01/2019
1	Atherosclerotic Plaque (Atheroma) 11/2018
1	Atherosclerosis 11/2018
1	Chronic Renal Insufficiency 01/2018
1	Breast Neoplasms (Breast Cancer) 03/2017
1	Fatty Liver 01/2017
1	Avian Sarcoma 12/2016
1	Portal Hypertension 03/2016

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2010
7	Biomarkers (Surrogate Marker)IBA 01/2019 - 12/2015
5	CateninsIBA 01/2022 - 11/2013
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2021 - 05/2006
4	ChemokinesIBA 01/2022 - 03/2017
4	CytokinesIBA 01/2020 - 09/2015
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 12/2015
3	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2019 - 12/2016
3	Proliferating Cell Nuclear Antigen (PCNA)IBA 05/2010 - 05/2006
2	Biological ProductsIBA 01/2022 - 01/2021
2	Pharmaceutical PreparationsIBA 01/2019 - 09/2015
2	Toll-Like Receptor 4IBA 01/2019 - 12/2016
2	Platelet-Derived Growth FactorIBA 01/2019 - 09/2013
2	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2018 - 11/2013
2	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 03/2017
2	Calcium-Binding ProteinsIBA 01/2016 - 09/2011
2	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2010 - 05/2006
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2022
1	ChitosanIBA 04/2022
1	Hyaluronic Acid (Hyaluronan)IBA 04/2022
1	Lactose FDA LinkGeneric 04/2022
1	Connective Tissue Growth FactorIBA 01/2022
1	pevonedistatIBA 01/2022
1	AdipokinesIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 04/2021
1	AntigensIBA 04/2021
1	obeticholic acidIBA 01/2020
1	Matrix Metalloproteinases (MMPs)IBA 01/2020
1	Aurora KinasesIBA 01/2019
1	navitoclaxIBA 01/2019
1	Protein Kinases (Protein Kinase)IBA 01/2019
1	Conditioned Culture MediaIBA 01/2019
1	Vascular Endothelial Growth Factor CIBA 01/2019
1	IncretinsIBA 01/2019
1	InflammasomesIBA 01/2019
1	Apolipoproteins E (ApoE)IBA 11/2018
1	LipidsIBA 11/2018
1	Histone Deacetylase InhibitorsIBA 10/2018
1	Valproic Acid (Depakote)FDA LinkGeneric 10/2018
1	CXCR ReceptorsIBA 01/2018
1	Chemokine CXCL10IBA 01/2018
1	Keratin-19 (Keratin 19)IBA 01/2018
1	EnzymesIBA 01/2018
1	Monomeric GTP-Binding ProteinsIBA 01/2018
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	Ligases (Synthetase)IBA 01/2018
1	N- (1- (3- (4- ethoxyphenyl)- 4- oxo- 3,4- dihydropyrido(2,3- d)pyrimidin- 2- yl)ethyl)- N- pyridin- 3- ylmethyl- 2- (4- trifluoromethoxyphenyl)acetamideIBA 01/2018
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018
1	ChromatinIBA 01/2018
1	UbiquitinIBA 01/2018
1	Choline (Choline Chloride)IBA 01/2017
1	ResveratrolIBA 01/2017
1	Methionine (L-Methionine)FDA Link 01/2017
1	LipopolysaccharidesIBA 12/2016
1	src-Family KinasesIBA 12/2016
1	EndotoxinsIBA 12/2016
1	Clodronic Acid (Clodronate)IBA 03/2016
1	CollagenIBA 03/2016

Therapy/Procedure

10	Therapeutics 04/2021 - 01/2017
3	Drug Therapy (Chemotherapy) 01/2018 - 09/2015
1	Ligation 01/2019
1	Immunotherapy 01/2018
1	Precision Medicine 01/2018
1	Organ Transplantation 01/2018